Mal-amido-PEG2-NHS ester

Mal-amido-PEG2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules[1][2].

Product Specifications

CAS Number

[955094-26-5]

UNSPSC

12352203

Hazard Statement

H302, H315, H319, H335

Target

ADC Linker

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mal-amido-peg2-nhs-ester.html

Purity

99.80

Solubility

10 mM in DMSO

Smiles

O=C(CCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)ON2C(CCC2=O)=O

Molecular Formula

C18H23N3O9

Molecular Weight

425.39

Precautions

H302, H315, H319, H335

References & Citations

[1]Hansen AM, et al. Microwave-assisted solid-phase synthesis of antisense acpP peptide nucleic acid-peptide conjugates active against colistin- and tigecycline-resistant E. coli and K. pneumoniae. Eur J Med Chem. 2019 Apr 15;168:134-145.|[2]Zhang ge, et al. Preparation and application of FAPalpha activated polypeptide magnetic nanosphere compound used for diagnosis of tumors. CN105524141A