DHFR-IN-21

DHFR-IN-21 (compund 5p) is a dihydrofolate reductase (DHFR) inhibitor[1].

Product Specifications

UNSPSC

12352005

Target

Dihydrofolate reductase (DHFR)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dhfr-in-21.html

Smiles

S=C(N/N=C/C1=CC=C(N2CCCCC2)C=C1)NC3=CC=CC([N+]([O-])=O)=C3

Molecular Formula

C19H21N5O2S

Molecular Weight

383.47

References & Citations

[1]Aftab H, et al. Design, synthesis, in vitro and in silico studies of novel piperidine derived thiosemicarbazones as inhibitors of dihydrofolate reductase. Sci Rep. 2024 Sep 30;14 (1) :22645.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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