DHFR-IN-21
DHFR-IN-21 (compund 5p) is a dihydrofolate reductase (DHFR) inhibitor[1].
Product Specifications
UNSPSC
12352005
Target
Dihydrofolate reductase (DHFR)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dhfr-in-21.html
Smiles
S=C(N/N=C/C1=CC=C(N2CCCCC2)C=C1)NC3=CC=CC([N+]([O-])=O)=C3
Molecular Formula
C19H21N5O2S
Molecular Weight
383.47
References & Citations
[1]Aftab H, et al. Design, synthesis, in vitro and in silico studies of novel piperidine derived thiosemicarbazones as inhibitors of dihydrofolate reductase. Sci Rep. 2024 Sep 30;14 (1) :22645.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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