Perfluorodecalin

Perfluorodecalin liquids are largrly used in vitreoretinal surgery. Perfluorodecalin with tamponade lasting more than two days is detrimental to the retina in the case of rabbit. Perfluorodecalin can be used for the research of giant retinal tears[1][2]. Perfluorodecalin is a non-toxic, non-flammable, thermally stable, non-bio-accumulating O2-carrier and used as artificial blood[3]. Perfluorodecalin enhances bone regeneration and cell viability[4][5].

Product Specifications

CAS Number

[306-94-5]

Product Name Alternative

PP 5; Perfluorodecahydronaphthalene

UNSPSC

12352211

Hazard Statement

H226

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Purity

98.0

Solubility

DMSO : 66.67 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

FC12C(F)(F)C(F)(F)C(F)(F)C(F)(F)C1(F)C(F)(F)C(F)(F)C(F)(F)C2(F)F

Molecular Formula

C10F18

Molecular Weight

462.08

Precautions

H226

References & Citations

[1]Orzalesi N, et al. Experimental short-term tolerance to perfluorodecalin in the rabbit eye: a histopathological study. Curr Eye Res. 1998;17 (8) :828-835. |[2]Bourke RD, et al. Experimental long-term vitreous replacement with purified and nonpurified perfluorodecalin. Am J Ophthalmol. 1994;118 (3) :403-404.|[3]Spahn DR. Blood substitutes. Artificial oxygen carriers: perfluorocarbon emulsions. Crit Care. 1999;3 (5) :R93-7.|[4]Tamimi F, et al., Perfluorodecalin and bone regeneration. Eur Cell Mater. 2013 Jan 2;25:22-36.|[5]Rodriguez-Brotons A, et al., Comparison of Perfluorodecalin and HEMOXCell as Oxygen Carriers for Islet Oxygenation in an In Vitro Model of Encapsulation. Tissue Eng Part A. 2016 Dec;22 (23-24) :1327-1336.