SID 3712249

SID 3712249 (MiR-544 Inhibitor 1) is a miR-544 biogenesis inhibitor. SID 3712249 binds directly to the precursor miRNA. SID 3712249 blocks production of the mature microRNA and decreases miR-544, HIF-1α, and ATM transcripts. SID 3712249 can be used in the research of cancers, such as breast cancer[1].

Product Specifications

CAS Number

[522606-67-3]

Product Name Alternative

MiR-544 Inhibitor 1

UNSPSC

12352005

Hazard Statement

H302

Target

Apoptosis; MicroRNA

Type

Reference compound

Related Pathways

Apoptosis; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/SID-3712249.html

Purity

99.26

Solubility

DMSO : 16.67 mg/mL (ultrasonic)

Smiles

NC1=C2C(C=C(N3CCCC3)N=C2N)=C(C#N)C(N4CCCC4)=N1

Molecular Formula

C17H21N7

Molecular Weight

323.40

Precautions

H302

References & Citations

[1]Christopher L Haga, et al. Small Molecule Inhibition of miR-544 Biogenesis Disrupts Adaptive Responses to Hypoxia by Modulating ATM-mTOR Signaling. ACS Chem Biol. 2015 Oct 16;10 (10) :2267-76.