STS-E412
STS-E412 is a selective activator of tissue-protective EPO receptor (including EPOR and CD131) . STS-E412 can be used for research of neurodegenerative diseases and organ protection[1].
Product Specifications
CAS Number
[1609980-39-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
JAK
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sts-e412.html
Concentration
10mM
Purity
99.72
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CC1=CC(C)=NC2=NC(OCCOC3=CC=C(Cl)C=C3)=NN12
Molecular Formula
C15H15ClN4O2
Molecular Weight
318.76
Precautions
H302, H315, H319
References & Citations
[1]Miller JL, et al. Discovery and Characterization of Nonpeptidyl Agonists of the Tissue-Protective Erythropoietin Receptor. Mol Pharmacol. 2015 Aug;88 (2) :357-67.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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