(±)5-HETE lactone
Product Specifications
UNSPSC Description
(±)5-HETE lactone is the racemate of 5-HETE lactone. 5-HETE lactone is a metabolite generated by a series of enzymatic reactions of arachidonic acid, and is also a substrate of paraoxonase-1 (PON1). 5-HETE lactone can be used in the study of B cell activation[1][2].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/racemic-5-hete-lactone.html
Solubility
10 mM in DMSO
Smiles
CCCCC/C=C\C/C=C\C/C=C\C=C\C1OC(CCC1)=O
Molecular Weight
302.45
References & Citations
[1]Tao C, et al. Reactivity of tricarbonyl (pentadienyl) iron (1+) cations: enantioselective synthesis of 5-HETE methyl ester[J]. The Journal of Organic Chemistry, 1993, 58(8): 2134-2143.|[2]Picardo C M. The hydrolysis of 5-HETE lactone by paraoxonase 1 and its stability in serum[M]. 2007.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-130220/racemic-5-HETE-lactone-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-130220/
Clinical Information
No Development Reported
CAS Number
81517-87-5
Curated Selection
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