(+)-U-50488 (hydrochloride)
Product Specifications
UNSPSC Description
(+)-U-50488 (hydrochloride) (+)-Trans-(1R,2R)-U-50488 hydrochloride) is a less active κ opioid receptor (KOR) agonist than the enantiomer of (-)-Trans-(1S,2S)-U-50488 (HY-15997)[1].
Target Antigen
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/plus-u-50488-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
O=C(N(C)[C@H]1[C@H](N2CCCC2)CCCC1)CC3=CC=C(Cl)C(Cl)=C3.[H]Cl
Molecular Weight
405.79
References & Citations
[1]DeCosta B, et al. Synthesis and absolute configuration of optically pure enantiomers of a kappa-opioid receptor selective agonist. FEBS Lett. 1987;223(2):335-339.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-15997A/plus-U-50488-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-15997A/
Clinical Information
No Development Reported
CAS Number
114528-81-3
Curated Selection
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