Human Lymphotactin/XCL1 (Recombinant)

<strong>Human Lymphotactin/XCL1</strong>_x000D_ <strong>Catalog number:</strong> B2010368_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Volume/Weight:</strong> 10 ug_x000D_ <strong>pH:</strong> 7.4 upon reconstitution_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Appearance:</strong> Powder_x000D_ <strong>Applications:</strong> highly pure Human Lymphotactin/XCL1 expressed in E. coli. This protein acts as a C class chemokine produced by T, NK, and NKT cells during infectious and inflammatory responses._x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> rHuLymphotactin/XCL1; ATAC; SCYC1_x000D_ <strong>Grade:</strong> Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Fox JC, Tyler RC, Guzzo C, Tuinstra RL, Peterson FC, Lusso P, Volkman BF._x000D_ Engineering Metamorphic Chemokine Lymphotactin/XCL1 into the GAG-Binding, HIV-_x000D_ Inhibitory Dimer Conformation. ACS Chem Biol. 2015 Nov 20;10(11):2580-8._x000D_ _x000D_ 2: Zavala-Flores LM, Villatoro-Hernandez J, Gamez-Escobedo A, Franco-Molina M,_x000D_ Rangel-Colmenero BR, Villanueva-Olivo A, Gutierrez-Puente Y, de Oca-Luna RM,_x000D_ Valdés-Flores J, Saucedo-Cardenas O. Production of biologically active human_x000D_ lymphotactin (XCL1) by Lactococcus lactis. Biotechnol Lett. 2009_x000D_ Feb;31(2):215-20._x000D_ _x000D_ 3: Leiter O, Bernas SN, Seidemann S, Overall RW, Horenburg C, Kowal S,_x000D_ Kempermann G, Walker TL. The systemic exercise-released chemokine_x000D_ lymphotactin/XCL1 modulates in vitro adult hippocampal precursor cell_x000D_ proliferation and neuronal differentiation. Sci Rep. 2019 Aug 14;9(1):11831._x000D_ _x000D_ 4: Zhang SM, Tian FJ, Zeng WH, Ma XL, Ren JB, Lin Y. XCL1-XCR1 pathway promotes_x000D_ trophoblast invasion at maternal-fetal interface by inducing MMP-2/MMP-9_x000D_ activity. Am J Reprod Immunol. 2018 Sep;80(3):e12990._x000D_ _x000D_ 5: Tuinstra RL, Peterson FC, Elgin ES, Pelzek AJ, Volkman BF. An engineered_x000D_ second disulfide bond restricts lymphotactin/XCL1 to a chemokine-like_x000D_ conformation with XCR1 agonist activity. Biochemistry. 2007 Mar_x000D_ 13;46(10):2564-73._x000D_ _x000D_ 6: Volkman BF, Liu TY, Peterson FC. Chapter 3. Lymphotactin structural dynamics._x000D_ Methods Enzymol. 2009;461:51-70._x000D_ _x000D_ 7: Endres M, Andreas K, Kalwitz G, Freymann U, Neumann K, Ringe J, Sittinger M,_x000D_ Häupl T, Kaps C. Chemokine profile of synovial fluid from normal, osteoarthritis_x000D_ and rheumatoid arthritis patients: CCL25, CXCL10 and XCL1 recruit human_x000D_ subchondral mesenchymal progenitor cells. Osteoarthritis Cartilage. 2010_x000D_ Nov;18(11):1458-66._x000D_ _x000D_ 8: Laudanski P, Lemancewicz A, Kuc P, Charkiewicz K, Ramotowska B, Kretowska M,_x000D_ Jasinska E, Raba G, Karwasik-Kajszczarek K, Kraczkowski J, Laudanski T._x000D_ Chemokines profiling of patients with preterm birth. Mediators Inflamm._x000D_ 2014;2014:185758._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/19274094/">9: Egesten A, Olin AI, Linge HM, Yadav M, Mörgelin M, Karlsson A, Collin M. SpeB_x000D_ of Streptococcus pyogenes differentially modulates antibacterial and receptor_x000D_ activating properties of human chemokines. PLoS One. 2009;4(3):e4769.</a>_x000D_ _x000D_ <strong>Products Related to Human Lymphotactin/XCL1 </strong> <a href="https://moleculardepot.com/product-category/Proteins/">: Proteins</a>