Thalidomide- (2) piperidine
Thalidomide- (2) piperidine (compound 9) is a potent E3 ligase ligand. Thalidomide- (2) piperidine can be used for synthesis of PROTACs[1].
Product Specifications
CAS Number
[2616553-33-2]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/androgen-receptor-degrader-2.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C2C=C3CNCCC3=C1)N(C(CC4)C(NC4=O)=O)C2=O.Cl
Molecular Formula
C16H16ClN3O4
Molecular Weight
349.77
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Shao MW, et, al. Androgen receptor protein degraders with a tricyclic cereblon ligand. WO2021231927A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Curated Selection
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