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Human IgG (Immunoglobulin Gamma Heavy Chain) (B-Cell Marker) (rIG266), CF640R conjugate, 0.1mg/mL

Recognizes a protein of 75 kDa, identified as gamma heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), mu (IgM), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

Synonyms

G1m Marker | G2m Marker | G3m Marker | G4m Marker | HDC | Heavy Chain Disease Protein | Human Immunglobulin G | Ig gamma1/2/3/4 Chain C Region | IGHG1 | IGHG2 | IGHG3 | IGHG4 | Immunoglobulin Heavy Constant 1/2/3/4

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

IGHG

Gene ID

3500; 3501; 3502; 3503

NCBI Gene ID

510635

UniProt

P01857, P01859, P01860, P01861

Swiss Prot

P01857, P01859, P01860, P01861

Host

Mouse

Species Reactivity

Human

Reactivity

IgG

Immunogen

Recombinant full-length human IGHG protein

Target Antigen

IgG

Clonality

Recombinant Monoclonal

Clone

RIG266

Type

Anti-Human Immunoglobulin|Primary

Source

Animal

Origin

Animal

Applications

IHC, FFPE (verified)

Field of Research

Cancer, Immunology, Inflammation

Positive Control

293T, Raji or hPBL cells. Tonsil or Spleen

Stability

2 years

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

75 kDa

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Notes

Protect from light

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Product Datasheet

https://cdn.gentaur.com/products/37/912910/datasheet/bnc401789-500.pdf

Product MSDS

https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf

Fragment

IgG1, kappa

Species

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

0.05% sodium azide (CAS 26628-22-8)

CAS Number

9007-83-4

Conjugate

CF640R

Curated Selection

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