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Anti-Mammaglobin (SCGB2A2) (Breast Cancer Marker) (MGB1/2000), CF488A conjugate

Mammaglobin is a 93 amino acid glycoprotein with homology to other secretoglobin-uteroglobin family members. It was originally identified as a breast cancer restricted biomarker by differential screening. Mammaglobin related to secretoglobin family that includes human uteroglobin and lipophilin. Mammaglobin antibody stains cytoplasm of normal breast epithelial cells as well as primary and metastatic breast carcinomas. Mammaglobin expression is absent in prostate, kidney, colon, rectum, small intestine, stomach, pancreas, lung, and thyroid tissues. Mammaglobin may be used as part of an immunohistochemical panel for determination of metastatic breast carcinoma and tumor of unknown primary origin.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

Synonyms

Mammaglobin-1 (MGB1); Mammaglobin-A; Secretoglobin family 2A member 2 (SCGB2A2); SG2A2; UGB2

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

SCGB2A2

Gene ID

4250

NCBI Gene ID

46452

UniProt

Q13296

Cellular Locus

Secreted (extracellular)

Host

Mouse

Species Reactivity

Human

Immunogen

Recombinant full-length human Mammaglobin (SCGB2A2) protein

Target Antigen

Mammaglobin

Clonality

Monoclonal

Isotype

IgG1 κ

Clone

MGB1/2000

Conjugation

CF488A

Disease

Tumor

Source

Animal

Applications

IHC, FFPE (verified) | WB (verified)

Validated Applications

IHC,FFPE,WB

Field of Research

Cancer

Positive Control

SK-BR-3 cells or Breast Carcinoma

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

18 kDa

Additionnal Information

Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Immunohistology (formalin): 0.1-0.2 ug/mL for 30 minutes at RT|Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes|Optimal dilution for a specific application should be determined by user

Shipping Conditions

Room temperature

Storage Conditions

4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

2 years

Product Datasheet

https://cdn.gentaur.com/products/37/910318/datasheet/bnc882000-100.pdf

Product MSDS

https://cdn.gentaur.com/products/37/910318/msds/bnc882000-100.pdf

CAS Number

9007-83-4

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