Neuropeptide AF (cattle)
Neuropeptide AF (cattle), an amidated octadecapeptide, is RFamide neuropeptide. Neuropeptide AF (cattle) acts as a ligand of Mas-related gene receptor A4 (MrgprA4) (Mas-related G-protein-coupled Receptor (MRGPR) ) (EC50 of ~60 nM) and MrgprC11 (EC50 of ~300 nM) . Neuropeptide AF (cattle) also activate to the G protein-coupled receptors NPFF1 (Neuropeptide Y Receptor) (EC50 of ~25-325 nM) and NPFF2 (EC50 of ~1-5 nM) . Neuropeptide AF (cattle) shows anti-opiate and related pain modulation effects[1][2].
Product Specifications
CAS Number
[99588-52-0]
UNSPSC
12352209
Target
Mas-related G-protein-coupled Receptor (MRGPR) ; Neuropeptide Y Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/neuropeptide-af-cattle.html
Solubility
10 mM in DMSO
Smiles
Molecular Formula
C89H130N24O24
Molecular Weight
1920.13
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
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