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Anti-TCF4 (Transcription Factor 4) (TCF4/1705), Biotin conjugate

This antibody recognizes a protein of 71 kDa, identified as Transcription Factor 4 (TCF4). It is a basic helix-loop-helix transcription factor. The protein recognizes an Ephrussi-box (E-box) binding site (CANNTG) - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome._x000D_ _x000D_ Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_ _x000D_

Product Specifications

Synonyms

bHLHb19; Class B basic helix-loop-helix protein 19; Immunoglobulin transcription factor 2; ITF-2; PTHS; SEF2; SL3-3 enhancer factor 2; TCF4; Transcription factor 4

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

TCF4

Gene ID

6925

NCBI Gene ID

605153

UniProt

P15884

Cellular Locus

Nucleus

Host

Mouse

Species Reactivity

Human

Immunogen

Recombinant human TCF4 protein fragment (around aa 365-671) (exact sequence is proprietary)

Target Antigen

TCF4

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

TCF4/1705

Conjugation

Biotin

Source

Animal

Applications

WB (verified)

Validated Applications

WB

Field of Research

Developmental biology, Transcription factors

Positive Control

HeLa or HepG2 cells. Bladder

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

71 kDa

Additionnal Information

ELISA: Use Ab at 2-4 ug/mL for coating; Order Ab without BSA; Western blot 1-2 ug/mL; Optimal dilution for a specific application should be determined.|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody

Shipping Conditions

Room temperature

Storage Conditions

4°C; Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

2 years

Product Datasheet

https://cdn.gentaur.com/products/37/908504/datasheet/bncb1705-500.pdf

Product MSDS

https://cdn.gentaur.com/products/37/908504/msds/bncb1705-500.pdf

CAS Number

9007-83-4

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