Cosdosiran
Product Specifications
UNSPSC Description
Cosdosiran is a chemically modified siRNA designed to temporarily inhibit expression of the caspase 2 protein and can be used for the study of nonarteritic anterior ischemic optic neuropathy and other optic neuropathies such as glaucoma that result in the death of retinal ganglion cells.?
Target Antigen
Caspase; Small Interfering RNA (siRNA)
Type
Oligonucleotides
Related Pathways
Apoptosis;Epigenetics
Applications
Neuroscience-Neurodegeneration
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/cosdosiran.html
Solubility
10 mM in H2O
Smiles
[Cosdosiran]
References & Citations
[1]Solano EC, Kornbrust DJ, Beaudry A, Foy JW, Schneider DJ, Thompson JD. Toxicological and pharmacokinetic properties of QPI-1007, a chemically modified synthetic siRNA targeting caspase 2 mRNA, following intravitreal injection. Nucleic Acid Ther. 2014;24(4):258-266. doi:10.1089/nat.2014.0489
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-158820/Cosdosiran-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-158820/
Clinical Information
Phase 3
CAS Number
1834560-88-1
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS2115176-01 0.1 mL
HRP-Linked Monoclonal Antibody to Anti-Mullerian Hormone (AMH)
Ask
View Details 
MBS2115176-02 0.2 mL
HRP-Linked Monoclonal Antibody to Anti-Mullerian Hormone (AMH)
Ask
View Details 
MBS2115176-03 0.5 mL
HRP-Linked Monoclonal Antibody to Anti-Mullerian Hormone (AMH)
Ask
View Details 
MBS2115176-06 5x 5 mL
HRP-Linked Monoclonal Antibody to Anti-Mullerian Hormone (AMH)
Ask
View Details