Anti-TACSTD2 / TROP2 (Epithelial Marker) (TACSTD2/2153)
TACSTD2 is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thyroglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. It plays a role intransducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TACSTD2
Gene ID
4070
NCBI Gene ID
23582
UniProt
P09758
Cellular Locus
Plasma membrane
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant fragment of human TACSTD2 protein (around aa 31-274) (exact sequence is proprietary)
Target Antigen
TACSTD2 | TROP2
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
TACSTD2/2153
Conjugation
Purified, with BSA
Source
Animal
Applications
IHC, FFPE (verified)
Validated Applications
IHC,FFPE
Field of Research
Cancer, Signal transduction
Positive Control
HT29 cells. Breast or Colon Carcinoma
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
40 kDa
Additionnal Information
Shipping Conditions
Room temperature
Storage Conditions
4°C; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/906218/datasheet/bnub2153-100.pdf
Product MSDS
https://cdn.gentaur.com/products/37/906218/msds/bnub2153-100.pdf
CAS Number
9007-83-4
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