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Anti-TACSTD2 / TROP2 (Epithelial Marker) (TACSTD2/2153)

TACSTD2 is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thyroglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. It plays a role intransducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

Synonyms

Cell surface glycoprotein Trop-2;Membrane Component Chromosome 1, Surface Marker 1 (M1S1);Pancreatic Carcinoma Marker Protein GA733-1;TROP2;Tumor-Associated Calcium Signal Transducer 2 (TACSTD2)

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

TACSTD2

Gene ID

4070

NCBI Gene ID

23582

UniProt

P09758

Cellular Locus

Plasma membrane

Host

Mouse

Species Reactivity

Human

Immunogen

Recombinant fragment of human TACSTD2 protein (around aa 31-274) (exact sequence is proprietary)

Target Antigen

TACSTD2 | TROP2

Clonality

Monoclonal

Isotype

IgG1 κ

Clone

TACSTD2/2153

Conjugation

Purified, with BSA

Source

Animal

Applications

IHC, FFPE (verified)

Validated Applications

IHC,FFPE

Field of Research

Cancer, Signal transduction

Positive Control

HT29 cells. Breast or Colon Carcinoma

Concentration

0.2 mg/mL

Buffer

PBS, 0.05% BSA, 0.05% azide

Molecular Weight

40 kDa

Additionnal Information

Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Immunohistology (formalin): 1-2 ug/mL for 30 minutes at RT|Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes|Optimal dilution for a specific application should be determined by user

Shipping Conditions

Room temperature

Storage Conditions

4°C; Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

2 years

Product Datasheet

https://cdn.gentaur.com/products/37/906218/datasheet/bnub2153-100.pdf

Product MSDS

https://cdn.gentaur.com/products/37/906218/msds/bnub2153-100.pdf

CAS Number

9007-83-4

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