Anti-Calnexin (Endoplasmic Reticulum Marker) (CANX/1541)
Calnexin is a type-I integral membrane protein of the endoplasmic reticulum (ER). It is a calcium-binding chaperone protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation._x000D_ Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_ _x000D_
Product Specifications
Synonyms
Calnexin; CANX; IP90; Major histocompatibility complex class I antigen-binding protein p88
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CANX
Gene ID
821
NCBI Gene ID
567968
UniProt
P27824
Cellular Locus
Endoplasmic reticulum
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant N-terminal fragment of human Calnexin protein (exact sequence is proprietary)
Target Antigen
Calnexin
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
CANX/1541
Conjugation
Purified, BSA-free
Source
Animal
Applications
Flow, intracellular | IF (verified) | IHC, FFPE (verified) | WB (verified)
Validated Applications
FC,IF,IHC,FFPE,WB
Field of Research
Chaperones, Immunology
Positive Control
HeLa, MCF-7 or U2OS cells. Kidney or small intestine.
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
67 kDa (predicted); 80-90 kDa (observed)
Additionnal Information
Shipping Conditions
Room temperature
Storage Conditions
-35°C to -5°C ; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/905897/datasheet/bnum1541-50.pdf
Product MSDS
https://cdn.gentaur.com/products/37/905897/msds/bnum1541-50.pdf
CAS Number
9007-83-4
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