Anti-IgG (Immunoglobulin Gamma Heavy Chain) (B-Cell Marker)
This antibody recognizes a protein of 75 kDa, identified as gamma heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), mu (IgM), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This antibody is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant._x000D_ _x000D_ Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_ _x000D_
Product Specifications
Synonyms
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
IGHG
Gene ID
3500 (IGHG1)|3501 (IGHG2)|3502 (IGHG3)|3503 (IGHG4)
NCBI Gene ID
510635
UniProt
P01857|P01859|P01860|P01861
Cellular Locus
Secreted (extracellular)
Host
Rabbit
Species Reactivity
Human
Immunogen
Purified human Ig Gamma Chain
Target Antigen
Human IgG Heavy Chain
Clonality
Polyclonal
Isotype
IgG κ
Conjugation
Purified, BSA-free
Disease
Tumor
Source
Animal
Applications
IHC, FFPE (verified)
Validated Applications
IHC,FFPE
Field of Research
Cancer, Immunology, Inflammation
Positive Control
293T, Raji or hPBL cells. Tonsil or Spleen
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
75 kDa
Additionnal Information
Shipping Conditions
Room temperature
Storage Conditions
-35°C to -5°C ; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/905721/datasheet/bnum0728-50.pdf
Product MSDS
https://cdn.gentaur.com/products/37/905721/msds/bnum0728-50.pdf
CAS Number
9007-83-4
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