Ozuriftamab vedotin
Product Specifications
UNSPSC Description
Ozuriftamab vedotin (BA3021), an antibody-drug conjugate (ADC), is a conditionally active biologic (CAB) anti-receptor tyrosine kinase orphan receptor 2 (ROR2) humanized monoclonal antibody Ozuriftamab (HY-145626) conjugated to VcMMAE (HY-15575). Ozuriftamab vedotin has antitumor activities[1].
Target Antigen
Antibody-Drug Conjugates (ADCs); Microtubule/Tubulin
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ozuriftamab-vedotin.html
Smiles
[Ozuriftamab vedotin]
References & Citations
[1]Alan L. Ho, et al. Abstract PO-007: A phase 2 open-label study of conditionally active biologic, ozuriftamab vedotin (BA3021) in PD-1/L1 failure patients with recurrent or metastatic squamous cell carcinoma of the head and neck. Clin Cancer Res (2023) 29 (18_Supplement): PO-007.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-145627/Ozuriftamab-vedotin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-145627/
Clinical Information
Phase 2
CAS Number
2460400-11-5
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1364948-01 0.02 mg (E-Coli)
Recombinant Rhodoferax ferrireducens 7-cyano-7-deazaguanine synthase (queC)
Ask
View Details 
MBS1364948-02 0.1 mg (E-Coli)
Recombinant Rhodoferax ferrireducens 7-cyano-7-deazaguanine synthase (queC)
Ask
View Details 
MBS1364948-03 0.02 mg (Yeast)
Recombinant Rhodoferax ferrireducens 7-cyano-7-deazaguanine synthase (queC)
Ask
View Details MBS1364948-04 0.1 mg (Yeast)
Recombinant Rhodoferax ferrireducens 7-cyano-7-deazaguanine synthase (queC)
Ask
View Details MBS1364948-05 0.02 mg (Baculovirus)
Recombinant Rhodoferax ferrireducens 7-cyano-7-deazaguanine synthase (queC)
Ask
View Details