Azasetron
Azasetron ((Rac) -SENS-401 free base) is an antiemetic drug with 5-HT3 receptor antagonist activity. Azasetron is often used as a preventive measure for postoperative nausea and vomiting or chemotherapy-induced nausea and vomiting. Azasetron does not impair neutrophil chemotaxis or phagocytosis and does not scavenge O (-) (2) or H (2) O (2) generated by cell-free systems[1].
Product Specifications
CAS Number
[123040-69-7]
Product Name Alternative
(Rac) -SENS-401 (free base)
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/azasetron.html
Smiles
O=C(C1=CC(Cl)=CC2=C1OCC(N2C)=O)NC3CN4CCC3CC4
Molecular Formula
C17H20ClN3O3
Molecular Weight
349.81
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
References & Citations
[1]Effects of ondansetron, granisetron, ramosetron, and azasetron on human neutrophil functions
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
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