(RXR)4XB
Product Specifications
UNSPSC Description
(RXR)4XB is a cell-penetrating peptide, that binds the phosphorodiamidate morpholino oligomers (PMOs), forms peptide-conjugated PMOs (PPMOs), and improves the delivery of PMO into bacterial cells. (RXR)4XB-PMO conjugate prevents the formation of biofilms, inhibits Pseudomonas aeruginosa with MIC50 of 0.5 to 16 μM, and reduces the bacterial burden in mouse acute pneumonia models[1].
Target Antigen
Bacterial
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/rxr-4xb.html
Smiles
N=C(N)NCCC[C@H](N)C(NCCCCCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(NCCCCCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(NCCCCCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(NCCCCCC(N[C@@H](CCCNC(N)=N)C(NCCCCCC(NCCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Weight
1904.37
References & Citations
[1]Howard JJ, et al., Inhibition of Pseudomonas aeruginosa by Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers. Antimicrob Agents Chemother. 2017 Mar 24;61(4):e01938-16.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P10559/RXR-4XB-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P10559/
Clinical Information
No Development Reported
CAS Number
879010-15-8
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