Anti-SOX2 (Transcription Factor) (SOX2/1792), CF640R conjugate
SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. At present, 30 Sox genes have been identified. SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
SOX2
Gene ID
6657
NCBI Gene ID
518438
UniProt
P48431
Cellular Locus
Nucleus
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant human SOX2 protein fragment (aa176-305) (exact sequence is proprietary)
Target Antigen
SOX2
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
SOX2/1792
Conjugation
CF640R
Source
Animal
Applications
IHC, FFPE (verified) | WB (verified)
Validated Applications
IHC,FFPE,WB
Field of Research
Stem cells, Transcription factors
Positive Control
MCF-7 cells or Cervical carcinoma
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
34 kDa
Additionnal Information
Shipping Conditions
Room temperature
Storage Conditions
4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/897754/datasheet/bnc401792-500.pdf
Product MSDS
https://cdn.gentaur.com/products/37/897754/msds/bnc401792-500.pdf
CAS Number
9007-83-4
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