Tie2/CD202b Extracellular Domain Human Recombinant

<strong>Tie2/CD202b Extracellular Domain Human Recombinant </strong>_x000D_ <strong>Catalog number:</strong> B2016925_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 200 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 108.5 kDa_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> Angiopoietin-1 Receptor, Endothelial Tyrosine Kinase, Tunica Interna Endothelial Cell Kinase 2, Tyrosine-Protein Kinase Receptor TEK_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Wangler S, Peroglio M, Menzel U, Benneker LM, Haglund L, Sakai D, Alini M, Grad S. Mesenchymal Stem Cell Homing Into Intervertebral Discs Enhances the Tie2-positive Progenitor Cell Population, Prevents Cell Death, and Induces a Proliferative Response Spine (Phila Pa 1976). 2019 Dec 1;44(23):1613-1622._x000D_ 2: Achyut BR, Shankar A, Iskander AS, Ara R, Angara K, Zeng P, Knight RA, Scicli AG, Arbab AS. Bone marrow derived myeloid cells orchestrate antiangiogenic resistance in glioblastoma through coordinated molecular networks Cancer Lett. 2015 Dec 28;369(2):416-26._x000D_ 3: Teichert M, Milde L, Holm A, Stanicek L, Gengenbacher N, Savant S, Ruckdeschel T, Hasanov Z, Srivastava K, Hu J, Hertel S, Bartol A, Schlereth K, Augustin HG. Pericyte-expressed Tie2 controls angiogenesis and vessel maturation Nat Commun. 2017 Jul 18;8:16106._x000D_ 4: Du S, Qian J, Tan S, Li W, Liu P, Zhao J, Zeng Y, Xu L, Wang Z, Cai J. Tumor cell-derived exosomes deliver TIE2 protein to macrophages to promote angiogenesis in cervical cancer Cancer Lett. 2022 Mar 31;529:168-179._x000D_ 5: Duran CL, Borriello L, Karagiannis GS, Entenberg D, Oktay MH, Condeelis JS. Targeting Tie2 in the Tumor Microenvironment: From Angiogenesis to Dissemination Cancers (Basel). 2021 Nov 16;13(22):5730._x000D_ 6: Li Y, Liu P, Zhou Y, Maekawa H, Silva JB, Ansari MJ, Boubes K, Alia Y, Deb DK, Thomson BR, Jin J, Quaggin SE. Activation of Angiopoietin-Tie2 Signaling Protects the Kidney from Ischemic Injury by Modulation of Endothelial-Specific Pathways J Am Soc Nephrol. 2023 Jun 1;34(6):969-987._x000D_ 7: Zhang Y, Liu J, Zou T, Qi Y, Yi B, Dissanayaka WL, Zhang C. DPSCs treated by TGF-β1 regulate angiogenic sprouting of three-dimensionally co-cultured HUVECs and DPSCs through VEGF-Ang-Tie2 signaling Stem Cell Res Ther. 2021 May 10;12(1):281._x000D_ 8: Parikh SM. Angiopoietins and Tie2 in vascular inflammation Curr Opin Hematol. 2017 Sep;24(5):432-438._x000D_ 9: Parikh SM. The Angiopoietin-Tie2 Signaling Axis in Systemic Inflammation J Am Soc Nephrol. 2017 Jul;28(7):1973-1982._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/33072401">10: Nguyen QD, Heier JS, Do DV, Mirando AC, Pandey NB, Sheng H, Heah T. The Tie2 signaling pathway in retinal vascular diseases: a novel therapeutic target in the eye Int J Retina Vitreous. 2020 Oct 13;6:48. </a>_x000D_ _x000D_ <strong>Products Related to Tie2/CD202b Extracellular Domain Human Recombinant can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>