Anti-alpha-1 Antitrypsin

Alpha-1 Antitrypsin is a secreted serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Its aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin. Thus, defects in this gene can cause emphysema or liver disease.

Product Specifications

CAS Number

9007-83-4

Reactivity

Human

Immunogen

Purified recombinant full length human alpha-1 Antitrypsin expressed in E. coli

Clonality

Monoclonal

Type

Antibodies-Monoclonal

Applications

WB,IHC,ELISA,ICC/IF,Other

Concentration

100µg/100µl

Purity

The antibody was affinity-purified from hybridoma supernatant by affinity-chromatography.

Buffer

PBS, pH 7.4 with 0.05% sodium azide

Shipping Conditions

Ice Pack

Storage Conditions

This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Fragment

IgG2a

Specificity

Human alpha-1 Antitrypsin

Applications Notes

WB: 1:2000~1:5000 ELISA: 1:2000~1:10000 IHC: 1:200~1:500 IF: 1:200~1:500 Optimal dilutions should be calculated by the end user based on their specific application.