Anti-MRP1 / ABCC1 (Multidrug Resistance Related Protein 1) (MRP1/1343), CF640R conjugate
The two members of the large family of ABC transporters known to confer multidrug resistance in human cancer cells are the MDR1 P-glycoprotein and the multidrug-resistance protein MRP1. MRP1 is an integral membrane protein that contains an MDR-like core, an N-terminal membrane-bound region and a cytoplasmic linker, and it is expressed in various cerebral cells, as well as in lung, testis and peripheral blood.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ABCC1
Gene ID
4363
NCBI Gene ID
391464
UniProt
P33527
Cellular Locus
Plasma membrane
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant human full-length ABCC1
Target Antigen
ABCC1 | MRP1
Clonality
Monoclonal
Isotype
IgG1
Clone
MRP1/1343
Conjugation
CF640R
Disease
Tumor
Source
Animal
Field of Research
Cancer, Transporters
Positive Control
A549 cells. Colon, Endometrium, Ovary. Testis or Tonsil.
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
190 kDa
Additionnal Information
Shipping Conditions
Room temperature
Storage Conditions
4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/896487/datasheet/bnc401343-100.pdf
Product MSDS
https://cdn.gentaur.com/products/37/896487/msds/bnc401343-100.pdf
CAS Number
9007-83-4
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