8-CPT-2'-O-Me-cAMP
Product Specifications
UNSPSC Description
8-CPT-2'-O-Me-cAMP is a Rap1 activator. 8-CPT-2'-O-Me-cAMP enhances the retinal pigment epithelium barrier against the pathological choroidal endothelial cell invasion that occurs in macular degeneration[1].
Target Antigen
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein;MAPK/ERK Pathway
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/8-cpt-2-o-me-camp.html
Smiles
NC1=C2C(N([C@H]3[C@@H]([C@@]4([H])[C@](COP(O)(O4)=O)([H])O3)OC)C(SC5=CC=C(C=C5)Cl)=N2)=NC=N1
Molecular Weight
485.84
References & Citations
[1]Wittchen ES, et al. Rap1 GTPase activation and barrier enhancement in rpe inhibits choroidal neovascularization in vivo. PLoS One. 2013 Sep 10;8(9):e73070.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-116312/8-CPT-2-O-Me-cAMP-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-116312/
Clinical Information
No Development Reported
CAS Number
510774-50-2
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