Recombinant Human NRG4
Neuregulins (NDF, heregulin, GGF ARIA, or SMDF) are EGF-like growth and differentiation factors that signal through tyrosine kinase receptors of the ErbB family. The ErbB2 and ErbB4 receptors cooperate in transmission of neuregulin-1 signals in the heart, whereas ErbB2 and ErbB3 cooperate in neural crest cells.
Product Specifications
CAS Number
9000-83-3
Gene Name
NRG4
Gene Aliases
Pro-neuregulin-4, membrane-bound isoform, Pro-NRG4, NRG4 <br/>Recombinant Human Neuregulin-4 (NRG4)
Gene ID
145957
Accession Number
Q8WWG1
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method
Purity
>95% as determined by SDS-PAGE
Solubility
Function
The ED(50) was determined by the dose-dependent proliferation of Raji cells and was found to be <0.05ng/mL.
Molecular Weight
7
Shipping Conditions
Ambient Temperature
Storage Conditions
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 μm filtered PBS, pH 7.4 solution.
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