TRP1 (Tyrosinase Related Protein 1) (TA99 + TYRP1/807), Biotin conjugate, 0.1mg/mL
This antibody reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1) . It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TYRP1
Gene ID
7306
NCBI Gene ID
270279
UniProt
P17643
Swiss Prot
P17643
Host
Mouse
Species Reactivity
Human,Mouse
Reactivity
TRP1
Immunogen
SK-MEL-23 cells (TA99) ; Recombinant full-length human TYRP1 protein (TYRP1/807)
Target Antigen
TRP1
Clonality
Monoclonal
Clone
TA99 TYRP1/807
Type
Primary
Source
Animal
Origin
Animal
Field of Research
Cancer
Positive Control
SK-MEL-23, SK-MEL-19, SK-MEL-30 cells or Melanoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
75 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Product Datasheet
https://cdn.gentaur.com/products/37/893883/datasheet/bncb0808-500.pdf
Product MSDS
https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf
Fragment
IgG' s
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
CAS Number
9007-83-4
Conjugate
Biotin
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items