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Anti-TGF-beta (Transforming Growth Factor beta)(TGFB/510)

This MAb recognizes TGF beta 1, 2 and 3. TGFs inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells. Most breast lesions, benign and malignant, involve abnormal proliferation and altered architecture of stromal and/or epithelial elements.

Product Specifications

Synonyms

ARVD; BSC 1 cell growth inhibitor; CED; Cetermin; Diaphyseal dysplasia 1 (DPD1); Glioblastoma derived T cell suppressor factor (G TSF); Latency-associated peptide (LAP); Polyergin; Transforming growth factor beta 1 (TGF beta1 or TGFB1); TGF beta2 (TGFB2); TGF beta3 (TGFB3); TGFbeta (TGFB)

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

TFGB

Gene ID

7040; 7042; 7043

NCBI Gene ID

645227

UniProt

P01137; P10600; P61812

Cellular Locus

Secreted (extracellular)

Host

Mouse

Species Reactivity

Cow,Dog,Hamster,Human,Monkey,Mouse,Rat

Immunogen

Full length recombinant human TGF-beta2 protein

Target Antigen

TGF-Beta

Clonality

Monoclonal

Isotype

IgG1 κ

Clone

TGFB/510

Conjugation

Purified, with BSA

Source

Animal

Field of Research

Signal transduction

Positive Control

Ovarian carcinoma, lung tumor or skin. PC-3 cell line. Eahy926 cells.

Concentration

0.2 mg/mL

Buffer

PBS, 0.05% BSA, 0.05% azide

Molecular Weight

~13 kDa

Additionnal Information

For coating for ELISA, order Ab without BSA|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Optimal dilution and staining procedure for a specific application should be determined by user|Recommended starting concentrations for titration are 1-2 ug/mL for most applications, or 1 ug/million cells/100 uL for flow cytometry

Shipping Conditions

Room temperature

Storage Conditions

4°C; Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

2 years

Product Datasheet

https://cdn.gentaur.com/products/37/892813/datasheet/bnub0510-500.pdf

Product MSDS

https://cdn.gentaur.com/products/37/892813/msds/bnub0510-500.pdf

CAS Number

9007-83-4

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