Anti-TGFalpha(MF9)
This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. The staining with Ab-1 is completely blocked by the peptide used for raising this antibody. TGF-beta (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
EGF-like TGF; ETGF; TFGA; TGF Type 1; TGFA; Wa1; Waved 1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TGFA
Gene ID
7039
NCBI Gene ID
170009
UniProt
P01135
Cellular Locus
Secreted (extracellular)
Host
Mouse
Species Reactivity
Cow,Human,Mouse,Rat
Immunogen
A 17-amino acid synthetic peptide from the carboxyl-terminus of rat TGF?.
Target Antigen
TGF-Alpha
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
MF9
Conjugation
Purified, with BSA
Source
Animal
Applications
IHC, FFPE (verified)
Validated Applications
IHC,FFPE
Field of Research
Signal transduction
Positive Control
Jurkat or Ramos cells. Testicular Carcinoma
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
6 kDa
Additionnal Information
Shipping Conditions
Room temperature
Storage Conditions
4°C; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/892585/datasheet/bnub0644-500.pdf
Product MSDS
https://cdn.gentaur.com/products/37/892585/msds/bnub0644-500.pdf
CAS Number
9007-83-4
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