Anti-TGFalpha(1E8-G6)
This antibody reacts with the TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. The staining with this MAb is completely blocked by the peptide used for raising this antibody. TGF-beta (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.
Product Specifications
Synonyms
EGF-like TGF; ETGF; TFGA; TGF Type 1; TGFA; Wa1; Waved 1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TGFA
Gene ID
7039
NCBI Gene ID
170009
UniProt
P01135
Cellular Locus
Secreted (extracellular)
Host
Mouse
Species Reactivity
Human,Rabbit,Zebrafish
Immunogen
A 10-amino acid synthetic peptide (aa34-43; PPVAAAVVSH) from human TGF?.
Target Antigen
TGF-Alpha
Clonality
Monoclonal
Isotype
IgM κ
Clone
1E8-G6
Conjugation
Purified, with BSA
Source
Animal
Applications
IHC, FFPE (verified)
Validated Applications
IHC,FFPE
Field of Research
Signal transduction
Positive Control
Jurkat or Ramos cells. Testicular Carcinoma
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
6 kDa
Additionnal Information
Shipping Conditions
Room temperature
Storage Conditions
4°C; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/892547/datasheet/bnub0785-500.pdf
Product MSDS
https://cdn.gentaur.com/products/37/892547/msds/bnub0785-500.pdf
CAS Number
9007-83-4
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