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Anti-TAG-72 / CA72.4(CA72/145)

Recognizes an oncofetal antigen of 220 kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. The majority of human adenocarcinomas including colorectal, pancreatic, gastric, ovarian, endometrial, mammary, and non-small cell lung cancer display some cell populations that are positive for TAG72. About 60% of carcinoma patients express TAG72 in their sera. TAG72 is reportedly useful in distinguishing pulmonary adenocarcinomas from pleural mesotheliomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

Synonyms

CA72.4, Tumor associated glycoprotein 72

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

tag-72

Gene ID

182875

NCBI Gene ID

Not Known

UniProt

Not Known

Cellular Locus

Cytoplasmic|Plasma membrane

Host

Mouse

Species Reactivity

Human

Immunogen

Human CA72.4 protein

Target Antigen

CA72.4 | TAG-72

Clonality

Monoclonal

Isotype

IgG1 κ

Clone

CA72/145

Conjugation

Purified, with BSA

Disease

Tumor

Source

Animal

Field of Research

Cancer

Positive Control

Jurkat cells, Breast or lung carcinoma.

Concentration

0.2 mg/mL

Buffer

PBS, 0.05% BSA, 0.05% azide

Molecular Weight

220 kDa

Additionnal Information

For coating for ELISA, order Ab without BSA|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Optimal dilution and staining procedure for a specific application should be determined by user|Recommended starting concentrations for titration are 1-2 ug/mL for most applications, or 1 ug/million cells/100 uL for flow cytometry

Shipping Conditions

Room temperature

Storage Conditions

4°C; Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

2 years

Product Datasheet

https://cdn.gentaur.com/products/37/892356/datasheet/bnub0145-100.pdf

Product MSDS

https://cdn.gentaur.com/products/37/892356/msds/bnub0145-100.pdf

CAS Number

9007-83-4

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