Anti-TAG-72 / CA72.4(CA72/145)
Recognizes an oncofetal antigen of 220 kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. The majority of human adenocarcinomas including colorectal, pancreatic, gastric, ovarian, endometrial, mammary, and non-small cell lung cancer display some cell populations that are positive for TAG72. About 60% of carcinoma patients express TAG72 in their sera. TAG72 is reportedly useful in distinguishing pulmonary adenocarcinomas from pleural mesotheliomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
CA72.4, Tumor associated glycoprotein 72
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
tag-72
Gene ID
182875
NCBI Gene ID
Not Known
UniProt
Not Known
Cellular Locus
Cytoplasmic|Plasma membrane
Host
Mouse
Species Reactivity
Human
Immunogen
Human CA72.4 protein
Target Antigen
CA72.4 | TAG-72
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
CA72/145
Conjugation
Purified, with BSA
Disease
Tumor
Source
Animal
Field of Research
Cancer
Positive Control
Jurkat cells, Breast or lung carcinoma.
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
220 kDa
Additionnal Information
Shipping Conditions
Room temperature
Storage Conditions
4°C; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/892356/datasheet/bnub0145-100.pdf
Product MSDS
https://cdn.gentaur.com/products/37/892356/msds/bnub0145-100.pdf
CAS Number
9007-83-4
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