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Anti-Retinol Binding Protein-1(RBP/872)

Recognizes a protein of 21 kDa-25 kDa, identified as retinol binding protein-1 (RBP1). This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein post-transnationally and results in defective delivery and supply to the epidermal cells.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

Synonyms

Cellular retinol-binding protein I, CRBP1, CRBP2, RBP1, RBP2, RBP4, RBPC, Retinol binding protein 1, Retinol binding protein 1 cellular, Retinol binding protein 2 cellular, Retinol binding protein 4 plasma

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

RBP1

Gene ID

5947, 5948 & 5950

NCBI Gene ID

529571

UniProt

P02753, P09455; P50120

Cellular Locus

Secreted (extracellular)

Host

Mouse

Species Reactivity

Goat,Human,Monkey,Mouse,Rabbit,Rat

Immunogen

Recombinant human retinol binding protein-1 (RBP1)

Target Antigen

Retinol Binding Protein 1

Clonality

Monoclonal

Isotype

IgG1 κ

Clone

RBP/872

Conjugation

Purified, with BSA

Source

Animal

Applications

IHC, FFPE (verified)

Validated Applications

IHC,FFPE

Field of Research

Metabolism

Positive Control

Hepatic or ovarian carcinoma

Concentration

0.2 mg/mL

Buffer

PBS, 0.05% BSA, 0.05% azide

Molecular Weight

21-25 kDa

Additionnal Information

Immunohistology formalin-fixed 1-2 ug/mL|Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes|Immunofluorescence 1-2 ug/mL|Optimal dilution for a specific application should be determined by user

Shipping Conditions

Room temperature

Storage Conditions

4°C; Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

2 years

Product Datasheet

https://cdn.gentaur.com/products/37/891482/datasheet/bnub0872-100.pdf

Product MSDS

https://cdn.gentaur.com/products/37/891482/msds/bnub0872-100.pdf

CAS Number

9007-83-4

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