Anti-Renal Cell Carcinoma (Carbonic Anhydrase IX)(PN-15)
Carbonic anhydrase IX (carbonic anhydrase 9) is one of several carbolic anhydrases that vary in tissue distribution and localization. Carbonic anhydrases catalyze the interconversion of carbon dioxide and water into carbonic acid and bicarbonate and are found in all mammalian tissues. Carbonic anhydrase IX is a transmembrane protein that is not expressed in most healthy tissues, but is expressed in most renal cell carcinomas._x000D__x000D_Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_ _x000D_
Product Specifications
Synonyms
Carbonic anhydrase IX; Carbonic anhydrase 9; RCC-associated antigen G250; Carbonic dehydratase; CA-IX; Membrane antigen MN
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CA9
Gene ID
768
NCBI Gene ID
63287
UniProt
Q16790
Cellular Locus
Plasma membrane
Host
Mouse
Species Reactivity
Horse,Human
Immunogen
Microsomal fraction of human renal cortical tissue homogenate
Target Antigen
Carbonic Anhydrase IX
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
PN-15
Conjugation
Purified, with BSA
Disease
Tumor
Source
Animal
Applications
IHC, FFPE (verified)
Validated Applications
IHC,FFPE
Field of Research
Cancer, Metabolism
Positive Control
Normal kidney or renal cell carcinoma
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
55 kDa
Additionnal Information
Shipping Conditions
Room temperature
Storage Conditions
4°C; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/890987/datasheet/bnub0637-500.pdf
Product MSDS
https://cdn.gentaur.com/products/37/890987/msds/bnub0637-500.pdf
CAS Number
9007-83-4
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