Anti-p55;50 EBV-Early Antigen(1108-1)
Epstein-Barr virus (EBV), also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness. The EBV-induced early antigens (Ea) are among several antigen complexes that have been identified in EBV-infected cells. The Ea complex is composed of diffuse (Ea-D) and restricted (Ea-R) components. The activity of Ea-D is suppressed during latent infection. BMRF1, the gene that encodes for Ea-D, is closely associated with the gene encoding for EBV DNA polymerase, and Ea-D is essential for the activity of this polymerase. Ea-D forms a complex with EBV DNase and, together, they may play a role in viral replication._x000D__x000D_Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
EBNA1; EBV nuclear antigen 1; Epstein Barr nuclear antigen 1; Human Herpesvirus 4 (HHV4)
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
UniProt
Not Applicable
Cellular Locus
Nucleus
Host
Mouse
Species Reactivity
EBV
Target Antigen
p55;50 EBV Early Antigen
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
1108-1
Conjugation
Purified, with BSA
Source
Animal
Applications
IF (published) | IP (published) | WB (published)
Validated Applications
IF,IP,WB
Field of Research
Infectious disease, Virology
Positive Control
EBV-infected cells or tissues
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
50/55 kDa doublet
Additionnal Information
References & Citations
Shipping Conditions
Room temperature
Storage Conditions
4°C; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/889506/datasheet/bnub0103-100.pdf
Product MSDS
https://cdn.gentaur.com/products/37/889506/msds/bnub0103-100.pdf
CAS Number
9007-83-4
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