Anti-Adipophilin / Perilipin-2 (Marker of Obesity) (ADFP/1493), CF740 conjugate
Perilipin-2, also known as Adipophilin, belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This 48 kDa protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
Perilipin-2; Adipophilin; ADFP; ADRP; Adipose differentiation-related protein; Perilipin-2
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
PLIN2
Gene ID
123
NCBI Gene ID
3416
UniProt
Q99541
Cellular Locus
Cytoplasmic
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant human Adipophilin protein fragment (aa249-376) (exact sequence is proprietary)
Target Antigen
Adipophilin | Perilipin-2
Clonality
Monoclonal
Isotype
IgG2b λ
Clone
ADFP/1493
Conjugation
CF740
Source
Animal
Applications
IHC, FFPE (verified)
Validated Applications
IHC,FFPE
Field of Research
Endocrinology, Metabolism
Positive Control
HepG2 or JAR cells. Liver, Adrenal gland or Cerebellum.
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% rBSA, 0.05% azide
Molecular Weight
48 kDa
Additionnal Information
Shipping Conditions
Room temperature
Storage Conditions
4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/888754/datasheet/bnc741493-500.pdf
Product MSDS
https://cdn.gentaur.com/products/37/888754/msds/bnc741493-500.pdf
CAS Number
9007-83-4
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