Rabbit anti Human HSF-1
Product Specifications
Background
DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.
Synonyms
Heat shock factor Protein 1
UniProt
Q00613
Host
Rabbit
Species Reactivity
Human
Isotype
Ig
Conjugation
Affinity Purified
Type
Antigen Immunoaffinity Purified Polyclonal
Applications
WB, IHC
Purification Method
Antigen Immunoaffiinity Purification
Assay Principle
Antibody can be used for immunohistochemistry (2 µg/mL) and Western blotting (1-2 µg/mL). Optimal concentration should be evaluated by serial dilutions.
Stability
See expiration date on vial
Concentration
See vial for Concentration
Form
Provided as solution in phosphate buffered saline with 0,08% sodium azide
Precautions
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving Humans or animals.
References & Citations
1. Jin, X., et al. ‘Targeted deletion of Hsf1, 2, and 4 genes in mice.’ Methods Mol. Biol., 787, 1-20 (2011)
2. Kaitsuka, T., et al. ‘Transformation of eEF1Bdelta into heat-shock response transcription factor by alternative splicing.’ EMBO Rep., 12, 673-681 (2011)
Shipping Conditions
Ambient Temperature, freeze upon arrival
Storage Conditions
Product should be stored at -20ºC; Aliquot to avoid freeze/thaw cycles
Functional Analysis
WB
CAS Number
9007-83-4
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