Anti-Myosin, Smooth Muscle Heavy Chain(SMMS-1)
Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors._x000D__x000D_Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
AAT4; Myosin heavy chain 11 (MYH11); Myosin heavy chain 11 smooth muscle; Smooth muscle myosin heavy chain 11; Myosin-11; SM1; SM2; SMHC; SMMHC
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MYH11
Gene ID
4629
NCBI Gene ID
460109
UniProt
P35749
Cellular Locus
Cytoskeleton
Host
Mouse
Species Reactivity
Cat,Chicken,Cow,Dog,Guinea pig,Human,Pig,Rabbit,Rat
Immunogen
Human uterus extract
Target Antigen
Myosin, Smooth-Muscle Heavy Chain
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
SMMS-1
Conjugation
Purified, BSA-free
Source
Animal
Applications
IHC, FFPE (verified)
Validated Applications
IHC,FFPE
Field of Research
Cytoskeleton
Positive Control
Uterus or normal breast
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
205 kDa (MHC-1) and 200 kDa (MHC-2)
Additionnal Information
Shipping Conditions
Room temperature
Storage Conditions
-35°C to -5°C ; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/887835/datasheet/bnum0893-50.pdf
Product MSDS
https://cdn.gentaur.com/products/37/887835/msds/bnum0893-50.pdf
CAS Number
9007-83-4
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