Sodium α-ketoisocaproate
Product Specifications
UNSPSC Description
Sodium α-ketoisocaproate, the transamination product of leucine, stimulates insulin secretion. Sodium α-ketoisocaproate (α-KIC) can either be oxidized to acetyl-CoA and acetoacetate, or it yields leucine through transamination with glutamate, forming α-KG (HY-44134)[1].
Target Antigen
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/sodium-α-ketoisocaproate.html
Purity
99.05
Smiles
[Na].O=C(O)C(=O)CC(C)C
Molecular Weight
152.12
References & Citations
[1]Mary E Rabaglia, et al. Alpha-Ketoisocaproate-induced hypersecretion of insulin by islets from diabetes-susceptible mice. Am J Physiol Endocrinol Metab. 2005 Aug;289(2):E218-24.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W017387/Sodium-α-ketoisocaproate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W017387/Sodium-α-ketoisocaproate-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
4502-00-5
Curated Selection
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