Anti-IgM Immunoglobulin(Cocktail), CF488A conjugate
Recognizes a protein of 75 kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant._x000D_ _x000D_ Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_ _x000D_
Product Specifications
Synonyms
AGM1; IGHM; Constant Region of Heavy Chain of IgM; Ig Mu Chain C Region
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
IGHM
Gene ID
3507
NCBI Gene ID
510635
UniProt
P01871; P20769
Cellular Locus
Plasma membrane|Secreted (extracellular)
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant heavy chain of human IgM (IM260 & IM373); Heavy chain of human IgM (ICO-30)
Target Antigen
Human IgM
Clonality
Monoclonal
Isotype
IgG
Clone
Cocktail
Conjugation
CF488A
Disease
Tumor
Source
Animal
Applications
IHC, FFPE (verified)
Validated Applications
IHC,FFPE
Field of Research
Cancer, Immunology, Inflammation
Positive Control
293T, Raji or hPBL cells. Tonsil or Spleen
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
50-75 kDa
Additionnal Information
Shipping Conditions
Room temperature
Storage Conditions
4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/883438/datasheet/bnc880762-100.pdf
Product MSDS
https://cdn.gentaur.com/products/37/883438/msds/bnc880762-100.pdf
CAS Number
9007-83-4
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