Anti-HSP60(HSPD1/875)
Recognizes a 60 kDa protein, identified as the heat shock protein 60 (hsp60). A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (HSPs), more appropriately called as stress response proteins (SRPs). hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial hsp60, but also against its mammalian homolog.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
HSPD1
Gene ID
3329
NCBI Gene ID
595053
UniProt
P10809
Cellular Locus
Mitochondria
Host
Mouse
Species Reactivity
Chicken,Guinea pig,Hamster,Human,Monkey,Mouse,Pig,Rat
Immunogen
Recombinant human HSPD1 protein
Target Antigen
HSP60
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
HSPD1/875
Conjugation
Purified, BSA-free
Source
Animal
Applications
IF (verified) | IHC, FFPE (verified)
Validated Applications
IF,IHC,FFPE
Field of Research
Autoimmunity, Heat shock proteins, Immunology, Inflammation
Positive Control
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
60 kDa
Additionnal Information
Shipping Conditions
Room temperature
Storage Conditions
-35°C to -5°C ; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/882667/datasheet/bnum0875-50.pdf
Product MSDS
https://cdn.gentaur.com/products/37/882667/msds/bnum0875-50.pdf
CAS Number
9007-83-4
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