Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-HSP60(HSPD1/780), CF640R conjugate

Recognizes a 60 kDa protein, identified as the heat shock protein 60 (hsp60). A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (HSPs), more appropriately called as stress response proteins (SRPs). Hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial hsp60, but also against its mammalian homolog.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

Synonyms

60kDa chaperonin; 60kDa heat shock protein mitochondrial; Chaperonin; 60-KD (CPN60); GROEL; HLD4; HSP65; HSPD1; HuCHA60; Mitochondrial matrix protein P1; P60 lymphocyte protein; Short heat shock protein 60 Hsp60s1; Spastic paraplegia 13 (SPG13)

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

HSPD1

Gene ID

3329

NCBI Gene ID

595053

UniProt

P10809

Cellular Locus

Mitochondria

Host

Mouse

Species Reactivity

Chicken,Cow,Dog,Hamster,Human,Monkey,Mouse,Pig,Rabbit,Rat,Sheep

Immunogen

Recombinant human HSPD1 protein

Target Antigen

HSP60

Clonality

Monoclonal

Isotype

IgG1 κ

Clone

HSPD1/780

Conjugation

CF640R

Source

Animal

Applications

IF (verified) | IHC, FFPE (verified) | WB (verified)

Validated Applications

IF,IHC,FFPE,WB

Field of Research

Autoimmunity, Heat shock proteins, Immunology, Inflammation

Positive Control

HeLa or HepG2 cells. Synovial biopsies from patients with juvenile chronic arthritis. Synovial lining layer is strongly positive for hsp60. Breast carcinoma.

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

60 kDa

Additionnal Information

Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Immunofluorescence: 0.5-1 ug/mL|Immunohistology formalin-fixed 0.5-1 ug/mL|Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes|Flow Cytometry 0.5-1 ug/million cells/0.1 mL|Western blotting 0.25-0.5 ug/mL|Optimal dilution for a specific application should be determined by user

Shipping Conditions

Room temperature

Storage Conditions

4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

2 years

Product Datasheet

https://cdn.gentaur.com/products/37/882650/datasheet/bnc400780-100.pdf

Product MSDS

https://cdn.gentaur.com/products/37/882650/msds/bnc400780-100.pdf

CAS Number

9007-83-4

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Rat Monoclonal CEACAM2 Antibody (935610) [Janelia Fluor 549]
FAB9214I 0.1 mL

Rat Monoclonal CEACAM2 Antibody (935610) [Janelia Fluor 549]

Ask
View Details
Human MYO9B knockdown cell line
ABC-KD9777 1 Vial

Human MYO9B knockdown cell line

Ask
View Details
2,3,4-Tribenzoyl-L-rhamnopyranose
C50723-1G 1 Unit

2,3,4-Tribenzoyl-L-rhamnopyranose

Ask
View Details
Annexin VII (A-1) Alexa Fluor® 790
sc-17815 AF790 200 µg/mL

Annexin VII (A-1) Alexa Fluor® 790

Ask
View Details
Anti-Glycosaminoglycans/GAGs Antibody (SAA2198), PerCP
FGN53814 100 Tests

Anti-Glycosaminoglycans/GAGs Antibody (SAA2198), PerCP

Ask
View Details
KRT37 Human qPCR Primer Pair (NM_003770)
HP207228 200 Reactions

KRT37 Human qPCR Primer Pair (NM_003770)

Ask
View Details