PSB-SB-1203

PSB-SB-1203 (Compound 25b) is a dual CB1/CB2 ligand that blocks CB1 but activates CB2 receptors (CB1 Ki 0.244 μM; CB2 Ki 0.210 μM, EC50 0.054 μM) . PSB-SB-1203 is promising for research of obesity and cancers[1].

Product Specifications

CAS Number

[1399049-80-9]

UNSPSC

12352005

Target

Cannabinoid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Cancer; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/psb-sb-1203.html

Smiles

O=C1OC2=C(C=C1CC3=C(O)C=CC=C3)C(O)=CC(C(C)(CCCCCC)C)=C2

Molecular Formula

C25H30O4

Molecular Weight

394.50

References & Citations

[1]Rempel V, et al. 7-Alkyl-3-benzylcoumarins: a versatile scaffold for the development of potent and selective cannabinoid receptor agonists and antagonists. J Med Chem. 2012 Sep 27;55 (18) :7967-77.