HER-2 / CD340 (HRB2/273), 1mg/mL
This MAb is specific to c-erbB-2/HER-2 and shows minimal cross-reaction with other members of the family. C-erbB-2/HER-2 is a member of the EGFR family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
P185, CD340, Verb b2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ERBB2
Gene ID
2064
NCBI Gene ID
446352
UniProt
P04626
Swiss Prot
P04626
Host
Mouse
Species Reactivity
Human
Reactivity
C-ErbB-2|CD340|HER-2|Neu
Immunogen
Recombinant extracellular domain of human HER-2 protein
Target Antigen
c-ErbB-2 | CD340 | HER-2 | Neu
Clonality
Monoclonal
Clone
HRB2/273
Type
Primary
Source
Animal
Origin
Animal
Applications
IF (verified)
Field of Research
Cancer, Signal transduction
Positive Control
SKBR-3 Cells or Breast Cancers.
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
185 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Product Datasheet
https://cdn.gentaur.com/products/37/881907/datasheet/bnum0273-50.pdf
Product MSDS
https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf
Fragment
IgG1, kappa
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
CAS Number
9007-83-4
Conjugate
Purified, BSA-free
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