Glycophorin A / CD235a (GYPA/280), 0.2mg/mL
Recognizes a sialoglycoprotein of 39 kDa, identified as glycophorin A (GPA) . It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
Blood group--MN locus; GPA; GPErik; GpMiIII; GPSAT; GYPA; MN sialoglycoprotein; MNS; PAS2; Sialoglycoprotein alpha
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
GYPA
Gene ID
2993 & 2994
NCBI Gene ID
434973; 654368
UniProt
P02724
Swiss Prot
P02724
Host
Mouse
Species Reactivity
Human
Reactivity
CD235a|Glycophorin-A
Immunogen
Recombinant human glycophorin A protein
Target Antigen
CD235a | Glycophorin-A
Clonality
Monoclonal
Clone
GYPA/280
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Hematology
Positive Control
Erythrocytes in any human tissues
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
39 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Product Datasheet
https://cdn.gentaur.com/products/37/880841/datasheet/bnub0280-500.pdf
Product MSDS
https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
CAS Number
9007-83-4
Conjugate
Purified, with BSA
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