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Glycophorin A / CD235a (GYPA/280), 0.2mg/mL

Recognizes a sialoglycoprotein of 39 kDa, identified as glycophorin A (GPA) . It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

Synonyms

Blood group--MN locus; GPA; GPErik; GpMiIII; GPSAT; GYPA; MN sialoglycoprotein; MNS; PAS2; Sialoglycoprotein alpha

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

GYPA

Gene ID

2993 & 2994

NCBI Gene ID

434973; 654368

UniProt

P02724

Swiss Prot

P02724

Host

Mouse

Species Reactivity

Human

Reactivity

CD235a|Glycophorin-A

Immunogen

Recombinant human glycophorin A protein

Target Antigen

CD235a | Glycophorin-A

Clonality

Monoclonal

Clone

GYPA/280

Type

Primary

Source

Animal

Origin

Animal

Applications

IHC, FFPE (verified) |WB (verified)

Field of Research

Hematology

Positive Control

Erythrocytes in any human tissues

Stability

2 years

Concentration

0.2 mg/mL

Buffer

PBS, 0.05% BSA, 0.05% azide

Molecular Weight

39 kDa

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Product Datasheet

https://cdn.gentaur.com/products/37/880841/datasheet/bnub0280-500.pdf

Product MSDS

https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf

Fragment

IgG1, kappa

Species

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)

CAS Number

9007-83-4

Conjugate

Purified, with BSA

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