Anti-Glycophorin A / CD235a(A63-B/C2)
Recognizes a sialoglycoprotein of 39 kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.
Product Specifications
Synonyms
Blood group--MN locus; GPA; GPErik; GpMiIII; GPSAT; GYPA; MN sialoglycoprotein; MNS; PAS2; Sialoglycoprotein alpha
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
GYPA
Gene ID
2993 & 2994
NCBI Gene ID
434973; 654368
UniProt
P02724
Cellular Locus
Plasma membrane
Host
Mouse
Species Reactivity
Human
Immunogen
Human erythrocytes treated with neuraminidase
Target Antigen
CD235a | Glycophorin-A
Clonality
Monoclonal
Isotype
IgM κ
Clone
A63-B/C2
Conjugation
Purified, BSA-free
Source
Animal
Field of Research
Hematology
Positive Control
Erythrocytes
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
39 kDa
Additionnal Information
References & Citations
Shipping Conditions
Room temperature
Storage Conditions
-35°C to -5°C ; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/880729/datasheet/bnum0935-50.pdf
Product MSDS
https://cdn.gentaur.com/products/37/880729/msds/bnum0935-50.pdf
CAS Number
9007-83-4
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