CP-690550A
CP-690550A is an analogue of Tofacitinib (HY-40354) . CP-690550A is a dual inhibitor of JAK2 and JAK3[1].
Product Specifications
CAS Number
[1243290-37-0]
UNSPSC
12352005
Target
JAK
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cp-690550a.html
Smiles
CN([C@H]1CN(CC[C@H]1C)C(CO)=O)C2=C3C(NC=C3)=NC=N2
Molecular Formula
C15H21N5O2
Molecular Weight
303.36
References & Citations
[1]Chrencik JE, et al. Structural and thermodynamic characterization of the TYK2 and JAK3 kinase domains in complex with CP-690550 and CMP-6. J Mol Biol. 2010 Jul 16;400 (3) :413-33.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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