Anti-EGFR(H9B4), CF594 conjugate
This MAb reacts with a cytoplasmic domain of EGFR. EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin & epiregulin._x000D_ _x000D_ Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_ _x000D_
Product Specifications
Synonyms
Erbb1; ERBB1; Errp; HER1; mENA; PIG61; Proto-oncogene c-ErbB-1; Receptor Tyrosine Protein Kinase; ErbB1; Urogastrone; wa2; Wa5
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
EGFR
Gene ID
1956
NCBI Gene ID
488293
UniProt
P00533
Cellular Locus
Plasma membrane
Host
Mouse
Species Reactivity
Human
Immunogen
Purified EGFR from A431 cells.
Target Antigen
EGFR
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
H9B4
Conjugation
CF594
Disease
Tumor
Source
Animal
Applications
WB (verified)
Validated Applications
WB
Field of Research
Cancer, Signal transduction
Positive Control
A431 cells, Breast or Bladder cancer
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
~170 kDa (wild type) and ~145 kDa (vIII variant)
Additionnal Information
Shipping Conditions
Room temperature
Storage Conditions
4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/879341/datasheet/bnc940642-500.pdf
Product MSDS
https://cdn.gentaur.com/products/37/879341/msds/bnc940642-500.pdf
CAS Number
9007-83-4
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