Anti-Cytokeratin, multi(KRT/457), CF594 conjugate
Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, including 59 kDa (CK4); 58 kDa (CK5); 56 kDa (CK6); 52 kDa (CK8); 56.5 kDa (CK10); 53 kDa (CK13) and 45 kDa (CK18). This is a broad-spectrum antibody, which has been reported to differentiate epithelial tumors from non-epithelial tumors. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
K1B; KRT1B; Keratin, type II cytoskeletal 1b; K77; CK-1B; Keratin 1B; Keratin-77; Cytokeratin-1B; Type-II Keratin Kb39
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
KRT4
Gene ID
3851 (CK4); 3852 (CK5); 3853 (CK6A); 3854 (CK6B); 286887 (CK6C); 3856 (CK8); 3858 (CK10); 3860 (CK13); 3875 (CK18) (Human)
UniProt
P02538 (CK6A); P04259 (CK6B); P13647 (CK5); P19013 (CK4); P48668 (CK6C)
Cellular Locus
Cytoskeleton
Host
Mouse
Species Reactivity
Cow,Frog,Goat,Guinea pig,Human,Monkey,Mouse,Pig,Rat
Immunogen
Keratin-enriched preparation from cultured human epithelial cells
Target Antigen
Cytokeratin, multi
Clonality
Monoclonal
Isotype
IgG1
Clone
KRT/457
Conjugation
CF594
Source
Animal
Applications
IHC, FFPE (verified)
Validated Applications
IHC,FFPE
Field of Research
Cancer, Cytoskeleton
Positive Control
A431 cells, Skin, Colon carcinoma
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
Multiple
Additionnal Information
Shipping Conditions
Room temperature
Storage Conditions
4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/878772/datasheet/bnc940457-100.pdf
Product MSDS
https://cdn.gentaur.com/products/37/878772/msds/bnc940457-100.pdf
CAS Number
9007-83-4
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