YM-16638
Product Specifications
UNSPSC Description
YM-16638 is an orally active leukotriene (LT) antagonist. YM-16638 can inhibit the production of LTC4, LTD4, and LTE4 in guinea pig trachea, with IC50 values of 0.05 μM, 0.16 μM, and 0.096 μM, respectively. YM-16638 has a dose-dependent inhibitory effect on antigen-induced early and late respiratory responses in allergic sheep[1].
Target Antigen
Leukotriene Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ym-16638.html
Smiles
O=C(O)CSC1=NN=C(SCCCOC2=CC=C(C(C)=O)C(O)=C2CCC)S1
Molecular Weight
442.57
References & Citations
[1]Tomioka K, et al. The effect of an orally active leukotriene (LT) antagonist YM-16638 on antigen-induced early and late airway responses in allergic sheep. Prostaglandins Leukot Essent Fatty Acids. 1989 Apr;36(1):43-7.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-19042/YM-16638-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-19042/
Clinical Information
No Development Reported
CAS Number
104073-72-5
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
NBP3-14272AF594 0.1 mL
Rabbit Monoclonal CFTR Antibody (CFTR/7003R) [Alexa Fluor 594]
Ask
View Details