Anti-Cytokeratin 5/8(C-50)
This antibody reacts with keratin 5 (58 kDa) and keratin 8 (52.5 kDa). Simple epithelia express cytokeratin 8 in combination with 18. On the other hand, basal cells of stratified epithelia express cytokeratin 5 paired with 14. This antibody therefore, reacts with a wide range of epithelia and their carcinomas._x000D__x000D_Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
KRT5
Gene ID
3852 (CK5); 3856 (CK8)
NCBI Gene ID
433845 (CK5); 533782; 708445 (CK8)
UniProt
P13647 (CK5); P05787 (CK8)
Cellular Locus
Cytoskeleton
Host
Mouse
Species Reactivity
Cow,Dog,Ferret,Hamster,Human,Mouse,Pig,Rat,Sheep
Immunogen
Cytoskeletal preparation from HeLa cells
Target Antigen
Cytokeratin 5/8
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
C-50
Conjugation
Purified, with BSA
Disease
Tumor
Source
Animal
Applications
IHC, FFPE (verified)
Validated Applications
IHC,FFPE
Field of Research
Cancer, Cytoskeleton
Positive Control
HepG2 or A431 cells. Skin or Squamous cell carcinoma
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
58 kDa (CK5); 52.5 kDa (CK8)
Additionnal Information
Shipping Conditions
Room temperature
Storage Conditions
4°C; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/877643/datasheet/bnub0948-500.pdf
Product MSDS
https://cdn.gentaur.com/products/37/877643/msds/bnub0948-500.pdf
CAS Number
9007-83-4
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